SIR 2024
Women's Health
Troy Sanders, MS
Medical Student
Interventional Radiology at David Geffen School of Medicine at UCLA
Financial relationships: Full list of relationships is listed on the CME information page.
Maureen Kohi, MD (she/her/hers)
Professor and Chair
University of North Carolina at Chapel Hill
Financial relationships: Full list of relationships is listed on the CME information page.
Antonio Moreno
Disclosure information not submitted.
Jimmy Guzman, BS
Research Assistant
David Geffen School of Medicine at UCLA
Disclosure information not submitted.
Jessie K. Stewart, MD (she/her/hers)
Assistant Professor, Interventional Radiology
David Geffen School of Medicine at UCLA
Financial relationships: Full list of relationships is listed on the CME information page.
Results: Intraluminal nBCA was observed in all embolized tubes at 2 days, 2 weeks, and 2 months post-procedure. In the cohort undergoing breeding trials, of which 8 of 11 rabbits achieved no pregnancies after 6 months, the majority of fallopian tubes demonstrated direct or indirect histopathologic evidence of embolization. Initial acute inflammation was present at 2 days post-embolization and was absent by 6 months, at which point granulomatous foreign body reaction was seen within the fallopian tubes. Mild fallopian tube fibrosis was observed in a minority of fallopian tubes over the study period.
Conclusion: Histopathologic analysis of rabbit fallopian tubes following long-segment embolization via a microcatheter reveals that either direct or indirect evidence of embolization was seen in the majority of tubes out to 6 months. Initial acute inflammation seen in rabbits sacrificed at day 2 decreased over time, with chronic, granulomatous processes indicative of foreign body reaction observed at 6 months post-embolization. Limited presence of tubal fibrosis noted in the selected sections may be due to sampling limitations.