SIR 2024
Imaging
Dilara J. Long, BA
MD-PhD student
Department of Biomedical Engineering, University of Arizona
Financial relationships: Full list of relationships is listed on the CME information page.
Bradford J. Wood, MD, FSIR
Director NIH Center for IO, Chief IR
NIH
Financial relationships: Full list of relationships is listed on the CME information page.
Lucas C. Struycken, MD
Fellow
Banner University Medical Center Tucson
Disclosure information not submitted.
Jennifer Barton, PhD
Principal Investigator; Director of BIO5 Institute
Department of Biomedical Engineering, University of Arizona
Disclosure information not submitted.
(1) To understand the principles and capabilities of Optical Coherence Tomography (OCT) in the context of Interventional Radiology (IR). (2) Review the clinical scenarios where OCT can provide valuable real-time imaging information.
Background:
Optical Coherence Tomography (OCT) is a high-resolution volumetric imaging modality that utilizes near-infrared light to provide cross-sectional histology-like images in real-time. The recent development of miniature catheter- and needle-based OCT probes offers an enhanced non-invasive alternative to visualize small caliber, tortuous, and difficult to access tissue microstructures and has found increasing utility in IR. This educational exhibit highlights the transformative potential of OCT to enhance diagnostic speed and accuracy, procedural precision, and patient care in IR procedures. The addition of fused OCT may provide multi-scale imaging that provides near field surface details in the context of conventional imaging. Furthermore, timely characterization of embolic drug delivery and post-ablation treatment margins could directly improve patient outcomes.
Clinical Findings/Procedure Details:
This exhibit will showcase structural and functional applications of OCT in IR procedures, including but not limited to endovascular atherosclerosis or device characterization, vulnerable plaque identification (lipid caps), stent implantation guidance, strut apposition assessment, thermal lesion depth/transmurality, and complication identification. Specific peripheral vascular disease applications include: Imaging vessel walls, detecting dissections, dynamic angiography, and optimizing endovascular therapies. Gastrointestinal procedures: Evaluate mucosal and submucosal lesion depth (polyps), guiding biopsy, and assess luminal stent placement. Neurointerventions: Assess intracranial aneurysms, visualize stent deployment, and guide clot retrieval. Biliary and pancreatic interventions: Characterize strictures, visualize stent placement, and assess drainage patency. Genitourinary interventions: Differentiate benign from malignant morphology, supplement selective salpingography and tubal catheterization, facilitate percutaneous renal ablation and biopsy.
Conclusion and/or Teaching Points:
After reviewing the exhibit, the viewer will gain deeper understanding of the techniques and applications for OCT implementation in a multitude of interventional radiology settings.