107 - Percutaneous versus Transjugular Random Renal Biopsy in High-Risk Patients: Comparison of Outcomes with Updated Results

Monday, April 13, 2026

4:12 PM - 4:21 PM ET

Author/Co-author(s)

HF

Hector Ferral, MD, FSIR (he/him/his)

Vice-Chairman of Research
Louisiana State University, New Orleans, United States
Dan Laney, MD

Assistant Professor - Clinical
LSU Health New Orleans, United States

Presenting Author(s)

Peyton Hopkins, MD

Research Fellow
LSUHSC - New Orleans, United States

Author/Co-author(s)

CD

Casey Duvall, MD

research fellow
LSUHSC New Orleans Department of Radiology, United States
RM

Rajesh Mohandas, MD

Chief- Nephrology and Hypertension
LSUHSC - New Orleans, United States
HL

Hieu Le, MD

Radiology Resident
LSUHSC - New Orleans, United States
KG

Katelyn Gill, BS

Medical Student
LSUHSC - New Orleans, United States

Purpose: The purpose of this retrospective study was to compare outcomes between percutaneous random renal biopsy (PRRB) versus Transjugular Random Renal Biopsy (TJRRB) in patients with high major bleeding risk scores (MBRS).

Materials and Methods: This is a retrospective, IRB approved and HIPPA compliant study. At our institution, TJRRB is considered for patients with morbid obesity or a calculated MBRS >15. The records of all patients who underwent PRRB between April 2020 and June 2024 were reviewed, and a selected cohort of patients with MBRS >15 was compared to patients who underwent transjugular random renal biopsy (TJRRB). Patient risk factors, technical success, diagnostic yield and complication rates were compared. Univariate data analyses were performed with p< 0.05 considered to be statistically significant.

Results: A total of 21 patients underwent TJRRB and 87 PRRB high risk patients were identified. Patient demographics and results are summarized in Table 1. Patients undergoing TJRB had a higher mean BMI and while patients undergoing PRRB had a higher mean MBRS. Major bleeding complications, biopsy diagnostic rate, and number of glomeruli per biopsy were similar. There were no deaths related to either technique.

Conclusion: This study showed that PRRB and TJRRB are comparable in safety and diagnostic yield in patients with high bleeding risk. BMI >35 may be the main indication for TJRRB.