Incidence of Aorta-related Adverse Events After TEVAR for Aortic Dissection: Comparative Analysis of Acute, Subacute, and Chronic Phases

Sunday, April 12, 2026

3:18 PM - 3:27 PM ET

Location: 701A

Presenting Author(s)

HK

Hiroaki Kato, MD, PhD

Clinical Fellow
Mie University Hospital, Radiology, Mie, Japan

Author/Co-author(s)

NK

Noriyuki Kato

Professor
Mie University Hospital, Radiology, Mie, Japan
TO

Takafumi Ouchi, MD (he/him/his)

Medical staff
Mie University Hospital, Radiology, Mie, Japan
TH

Takatoshi Higashigawa, MD, PhD

Physician
Mie University Hospital, Radiology, Mie, Japan
YY

Yuki Yamaoka, MD

Physician
Mie University Hospital, Radiology, Mie, Japan
KN

Ken Nakajima

Attending physician
Ise Red Cross Hospital, Radiology, Mie, Japan
SC

Shuji Chino

Manager
Ise Red Cross Hospital, Radiology, Mie, Japan
HI

Hisato Ito

Senior Lecturer
Mie University Hospital, Thoracic and Cardiovascular Surgery, Mie, Japan
TT

Toshiya Tokui

Manager
Ise Red Cross Hospital, Thoracic Surgery, Mie, Japan
TM

Toru Mizumoto

Manager
Anjo Kosei Hospital, Cardiovascular Surgery, Aichi, Japan
KO

Kensuke Oue

Manager
Kochi Health Sciences Center, Cardiovascular Surgery, Kochi, Japan
YI

Yasutaka Ichikawa, MD, PhD

Physician
Mie University Hospital, Radiology, Mie, Japan
HS

Hajime Sakuma, MD, PhD

Physician
Mie University Hospital, Radiology, Mie, Japan

Purpose: To compare the incidence of aorta-related adverse event according to the timing of thoracic endovascular aortic repair (TEVAR) for aortic dissection.

Materials and Methods: We retrospectively analyzed patients who underwent TEVAR for aortic dissection at four institutions between 2008 and 2024.

Results: A total of 148 patients (127 men, 21 women) were included. Of these, 36 were treated in the acute phase, 18 in the subacute phase, and 94 in the chronic phase. The 1- and 5-year overall survival rates were 77.7% and 52.9%, respectively.

In-hospital mortality and aorta-related adverse events were defined as early aorta-related adverse events (AAE), whereas late aorta-related death and AAEs were defined as late adverse events. The incidence of these events was compared among the acute, subacute, and chronic phase groups.

The incidence of early AAEs was 47.2% (17/36) in the acute group, 38.9% (7/18) in the subacute group, and 14.9% (14/94) in the chronic group. Overall comparison showed a significant difference (Fisher’s exact test, p = 0.0003). Pairwise analysis revealed a significant difference between the acute and chronic groups (p = 0.0008, after Bonferroni correction).

The incidence of late AAEs was 33.3% (12/36) in the acute group, 38.9% (7/18) in the subacute group, and 40.4% (38/94) in the chronic group. No significant differences were observed in the overall comparison (Fisher’s exact test, p = 0.77), and no pairwise comparisons reached statistical significance.

Conclusion: TEVAR for aortic dissection was associated with a higher incidence of early AAEs in the acute phase and a lower incidence in the chronic phase. In contrast, the incidence of late AAEs did not differ among groups, and careful postoperative follow-up is required in all patients.