110 - Transhepatic Portal Vein Closure Using AngioSeal: A Case Series

Purpose: Arterial closure is a critical aspect of vascular interventional radiology to prevent excess bleeding from arterial access. The purpose of this study was to evaluate off-label use of the AngioSeal arterial closure system for percutaneous portal vein access closure in patients undergoing hepatic vascular procedures.

Materials and Methods: Eight patients who underwent various hepatic vascular procedures had off-label closure of the percutaneous hepatic access sites using AngioSeal and were monitored afterwards for signs of hepatic bleeding or similar complications. Procedures included varix embolization, portal vein thrombectomy, and TIPS. AngioSeal size was either 6 French or 8 French.

Results: Eight patients received AngioSeal closure of percutaneous portal vein access for various procedures, including portal vein thrombectomy, varix embolization, and TIPS. One patient had AngioSeal closure done in two separate procedures. Seven patients were male and one was female. The median patient age was 56.38 years ranging from 46 years old to 61 years old. There were no procedure associated complications observed in any of the patients.

Conclusion: Off-label AngioSeal closure of percutaneous portal vein access appears to be a safe and effective procedure. Further studies are warranted to compare its potential effectiveness to other available alternatives in preventing post-procedural hepatic bleeding.