SIR 2024
Interventional Oncology
Shamar Young, MD
Associate professor and Chief of Interventional Radiology
University of Arizona
Financial relationships: Full list of relationships is listed on the CME information page.
Tiffany Shamas, BS (she/her/hers)
Medical Student
University of Arizona
Financial relationships: Full list of relationships is listed on the CME information page.
Lucas C. Struycken, MD
Fellow
Banner University Medical Center Tucson
Disclosure information not submitted.
Jack Hannallah, MD, MBA, MPH
Assistant Professor
University of Arizona
Disclosure information not submitted.
Daniel Goldberg, MD
Assistant Professor
University of Arizona - Tucson
Disclosure information not submitted.
Gregory J. Woodhead, MD, PhD
Assistant Professor, Interventional Radiology
University of Arizona
Disclosure information not submitted.
In total 47 patients underwent CA of 52 HCCs and 46 patients underwent MWA of 66 HCCs. The demographic data was only significant for differences in the alphafeto protein (median 11.3 (IQR:85.5) in CA vs 6.7 (IQR:8.2) MWA, p=0.012) there were no significant differences in the demographic variables. There was no significant difference in the number of incomplete ablations (4/52 7.7% in CA vs 9/66, 13.6% MWA, p=0.38) or local recurrences (11/52, 21.2% CA vs 13/66, 19.7% MWA p=0.98). The median local TTP was not reached but the mean was 49.5 (95%CI: 39.3-59.8) months for CA and 51.2 (95%CI: 43.5-58.9) months MWA. There was no significant difference in local TTP on Kaplan-Meier analysis between the two groups (HR: 0.65 (95%CI: 0.29-1.46), p=0.30. When evaluating overall TTP the median for CA was 16.2 months (95%CI: 5.4-43.9 months) as compared to 16.6 months (95%CI: 12.6-25.7) months for MWA. No significant differences were noted in overall TTP between the two cohorts on Kaplan-Meier analysis (0.99 (95%CI: 0.6-1.64), p=0.98). The median overall survival for the CA cohort was 44.1 (95%CI:19.6-45.4) months as compared to 77.3 (95%CI:29.3-77.3) months in the MWA cohort. When compared by Kaplan-Meier analysis there was no significant difference in overall survival between the two cohorts HR: 0.63 (95%CI:0.33-1.21), p=0.17.
Conclusion: No significant differences were noted in terms of incomplete ablation, local TTP, overall TTP, or overall survival in patients with HCC who underwent either CA or MWA.