SIR 2024
Pain Management/MSK
Lucas R. Cusumano, MD, MPH
resident
ucla
Financial relationships: Full list of relationships is listed on the CME information page.
Helen Albrecht, None
Undergraduate student
University of California, Los Angeles
Disclosure information not submitted.
Kara Masterson, MS, NP, RN
Clinical Nurse Practioner
UCLA Health
Disclosure information not submitted.
Scott Genshaft, MD
Associate Clinical Professor
UCLA Interventional Radiology
Disclosure information not submitted.
Jessie K. Stewart, MD (she/her/hers)
Assistant Professor, Interventional Radiology
David Geffen School of Medicine at UCLA
Financial relationships: Full list of relationships is listed on the CME information page.
Tyler E. Callese, MD
Resident Physician
UCLA
Financial relationships: Full list of relationships is listed on the CME information page.
Siddharth Padia, MD
Professor
David Geffen School of Medicine at UCLA
Financial relationships: Full list of relationships is listed on the CME information page.
Concerns may exist as to potential healing complications after total knee arthroplasty (TKA) following genicular artery embolization (GAE) for knee osteoarthritis (OA). This study evaluates the adverse events related to total knee arthroplasty (TKA) following GAE.
Materials and Methods:
This IRB-approved retrospective study analyzed 47 patients who underwent 48 TKA procedures following 48 GAEs (out of a total of 260 GAEs) performed for painful knee OA between January 2019 and July 2023. Post TKA follow-up records were available for 40 (83%) TKA procedures and were included in the analysis. Records were reviewed for the presence of post-procedure complications including wound healing which is a theoretical risk of TKA performed after GAE.
Results:
TKA was performed by one of 16 orthopedic surgeons at 10 hospitals. Mean time between GAE and TKA was 459 (± 332 days) days. Follow-up time after TKA was a mean of 361 (± 346) days. Four (8%) complications were seen following TKA procedures, including two (4%) wound healing adverse events. One patient developed a wound dehiscence four weeks post TKA requiring a subsequent incision and drainage procedure. One patient developed a small eschar seven weeks following TKA which was closed with a staple. Additional adverse events reported in two other patients were a stich abscess and fluid discharge at the surgical incision. The remaining 46 TKAs did not develop post procedure adverse events. There were no significant differences between mean age (64 vs. 70 years, P = 0.112), BMI (43 vs. 47, P = 0.333), Kellgren-Lawrence score (3 vs. 3, P = 0.669), and number of arteries treated (2 vs. 2, P = 0.697) between groups with and without adverse events following TKA, respectively.
Conclusion:
Adverse events related to GAE for patients undergoing TKA are low. GAE should not be considered a contraindication for future TKA, and may serve as a bridge in those trying to defer TKA to a future date.