SIR 2024
Embolization
Abhishek Goswami, MD
Resident
University of Chicago Medical Center
Financial relationships: Full list of relationships is listed on the CME information page.
Wali Badar, MD
Resident
University of Illinois at Chicago
Financial relationships: Full list of relationships is listed on the CME information page.
Qian Yu, MD (he/him/his)
Resident
University of Chicago
Financial relationships: Full list of relationships is listed on the CME information page.
Rosemary Uy-Palmer, NP
IR Nurse Practioner
University of Chicago Medical Center
Disclosure information not submitted.
Brendon Ross, DO, MS
Assistant Professor of Orthopedic Surgery and Rehabilitation Medicine
University of Chicago Medical Center
Disclosure information not submitted.
Magdalena Anitescu, MD, PhD
Professor of Anesthesia and Critical Care
University of Chicago Medical Center
Disclosure information not submitted.
Sara Wallace, MD
Assistant Professor of Orthopedic Surgery
University of Chicago Medical Center
Disclosure information not submitted.
A total of 26 limbs underwent GAE (13 left limb, 13 right limb), with baseline KOA severity of KL-2 (n=8), KL-3 (n=13), and KL-4 (n=5). In total, 76 arterial vessels were embolized with average volumes of 2.0 mL and 2.9 vessels per procedure. Target arteries included inferior lateral geniculate (n=19, 25.0%), inferior medial geniculate (n=18, 23.7%), descending geniculate (n=15, 19.7%), superior lateral geniculate (n=11, 14.5%), superior medial geniculate (n=11, 14.5%), lateral muscular branch (n=1, 1.3%), and recurrent anterior tibial branch (n=1, 1.3%). WOMAC scores (out of 96) and WOMAC pain subscores (out of 20) decreased after GAE, which were respectively 58.4 and 12.0 (n=26; 26) at baseline (BL), 34.5 and 6.5 (n=22; 20) at 1-month, and 29.5 and 5.1 (n=14; 14) at 3-month follow-up. No major complications occurred. Minor complications included procedure site erythema/edema/skin changes (n=11, 42.3%), puncture site hematoma (n=2, 7.7%), and hives (n=1, 3.8%).
Compared to BL, the decrease in total WOMAC and WOMAC pain subscores were statistically significant at 1-month (p = .001 for both) and 3-months (p < .001 for both). Differences from 1-month to 3-months did not reach statistical significance (p = .69 and .58, respectively).
Conclusion: GAE using 200 micron microspheres is safe and effective in treating medically refractory KOA in a predominantly African-American population.